Principles of Neural Science, 6th Edition

The gold standard of neuroscience texts, Principles of Neural Science, Sixth Edition, has been updated with hundreds of brand-new images and fully revised content in every chapter. Recognized as a Doody’s Core Title for 2023, this landmark reference has helped readers understand the link between the human brain and behavior for over 40 years. It emphasizes that all behavior is an expression of neural activity and that the future of clinical neurology and psychiatry hinges on advancements in neural science.

This new edition features:

• Unmatched coverage of the functions of nerves, brain, and mind.
• NEW chapters on:
  • The Computational Bases of Neural Circuits that Mediate Behavior
  • Brain-Machine Interfaces
  • Decision-Making and Consciousness
• NEW section on the neuroscientific principles underlying nervous system disorders.
• Expanded coverage of different forms of human memory.
• Highly detailed chapters on stroke, Parkinson’s disease, and multiple sclerosis.
• A total of 2,200 images, including 300 new color illustrations, diagrams, radiology studies, and PET scans.

The text is thoughtfully organized, beginning with an insightful overview of the interrelationships between the brain, nervous system, genes, and behavior. It is divided into nine sections:

• Part I: Overall Perspective – Overview of broad themes in neural science, anatomical organization, and genetic bases of nervous system function.
• Part II: Cell and Molecular Biology of Cells of the Nervous System – Basic properties of nerve cells, including signaling.
• Part III: Synaptic Transmission – Mechanisms of synaptic transmission, neuronal excitability, and neurotransmitter release.
• Part IV: Perception – Aspects of sensory perception and information processing in the central nervous system.
• Part V: Movement – Neural mechanisms of movement and the role of basal ganglia in motor actions and reinforcement learning.
• Part VI: The Biology of Emotion, Motivation, and Homeostasis – Neural mechanisms mediating homeostatic control, emotions, and motivation.
• Part VII: Development and the Emergence of Behavior – Development from embryonic differentiation to synapse formation and elimination.
• Part VIII: Learning, Memory, Language, and Cognition – Cellular mechanisms of memory storage, decision-making, and consciousness.
• Part IX: Diseases and Disorders of the Nervous System – Neural mechanisms underlying conditions such as autism spectrum disorder, epilepsy, schizophrenia, and anxiety.

This comprehensive approach provides an unparalleled perspective on the current state and future of neural science.